S1885
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S1885
Sigma
Suberic acid bis(N-hydroxysuccinimide ester)
≥95%, powder
| Synonym: | Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS) |
| CAS Number: | 68528-80-3 |
| Linear Formula: | C16H20N2O8 |
| Molecular Weight: | 368.34 |
| MDL number: | MFCD00049059 |
| PubChem Substance ID: | 24899500 |
Description
| Application | Homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Incorporates 8-atom linker. |
Properties
| assay | ≥95% |
| form | powder |
| solubility | chloroform: 50 mg/mL |
| DMF: soluble | |
| aqueous buffer: may require 5-10% organic solvent in coupling mixture. slightly soluble | |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
References
| reference | Loster, K., et al., Chemical cross-linking leads to two high molecular mass aggregates of rat α 1 β 1 integrin differing in their conformation but not in their composition. FEBS Lett. 373, 234, (1995) Abstract |
